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Health > Aging

Research shows lifestyle outweighs genetics for lifespan and healthspan. Evidence-based ways to slow biological aging that lift daily life right away: more energy, better mood, deeper sleep, sharper focus, better health, and, through clearer thinking and steadier emotions, better relationships.

Future of aging and health: emerging technologies in anti-aging medicine

the rapid advancements in anti-aging medicine, emphasizing the potential of wearables, implantable devices, and biological age clocks to transform healthcare. Remote monitoring, telemedicine, and...

Enhance brain health: strategies to slow brain aging and boost cognitive health

the molecular and lifestyle interventions to slow cognitive decline and diseases like Alzheimer's. Key points include the importance of longevity pathways (Sirtuins, AMPK, mTOR), the benefits of a...

Reverse cosmetic aging: improve skin, nails, and hair health

Harvard professor David Sinclair and co-host Matthew LaPlante discuss methods to slow or reverse cosmetic aging, focusing on skin, hair, and nails. They examine treatments such as hormone therapy,...

Cutting-edge interventions for longevity and age reversal

Advanced medical interventions for longevity, including stem cell therapy, testosterone replacement, human growth hormone (HGH), and cellular reprogramming. While testosterone and HGH provide...

Key supplements and drugs for longevity and overall health improvement

David Sinclair and Matthew LaPlante dive into various supplements and drugs believed to support longevity. Key substances include NAD boosters (NR and NMN), Metformin, resveratrol, fisetin, and...

Exercise, sauna and ice bath: exploring the health benefits of adversity mimetics, exercise, and temperature exposure

The importance of exercise and adversity mimetics in activating longevity pathways. David Sinclair explains how vigorous exercise, intermittent fasting, and exposure to temperature extremes (cold...

What to eat and when to eat

Intermittent Fasting (IF): Eating within a restricted time window, like 16–20 hours of fasting daily, helps activate longevity pathways, reduce body fat, and stabilize glucose levels. Over time,...

Aging is a controllable process that can be slowed and reversed

The podcast "Lifespan" by Dr. David Sinclair, a Harvard Medical School professor, explores the science of aging and how to live a longer, healthier life. Topics include breakthroughs in anti-aging...