Age-related changes in brain network connectivity and cognitive decline
A systematic review of resting-state functional brain networks across the adult lifespan shows that older adults exhibit reduced within-network and increased between-network functional connectivity, along with lower segregation, modularity, and efficiency. These changes, which often begin in the third or fourth decade of life, contribute to the cognitive decline commonly seen in aging. Higher-order networks, such as those involved in executive function, are particularly affected, while primary sensory and motor networks show more variability. These alterations suggest a shift towards a less specialized and more integrated brain network system in older age, with significant implications for cognitive performance.
https://onlinelibrary.wiley.com/doi/10.1111/psyp.14159
The brain retains significant capacity for rewiring and adaptability even after age 40, contradicting long-held beliefs that neuroplasticity declines sharply with age. This ability allows for continued learning, skill development, and cognitive resilience, provided individuals engage in challenging activities and maintain healthy lifestyles. Emphasizing mental fitness can help harness the brain’s lifelong potential for growth and change.
https://bigthink.com/neuropsych/great-brain-rewiring-after-age-40/
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