A study in mice suggests that the simple sugar 2-deoxy-D-ribose, which the body already makes as part of DNA, can restart hair growth that was shut down by testosterone. Its effect on hair length, thickness, and density matched the result seen with minoxidil, the main drug now used against pattern baldness. Scientists noticed the sugar’s power by chance while studying wound healing.
The sugar appears to work by sparking new blood-vessel growth around each hair root. Better blood flow brings oxygen and nutrients that help dormant follicles return to the active growth phase. Because 2-deoxy-D-ribose is cheap, stable, and already present in the body, researchers see it as a safer and more affordable option than current drug treatments, which can irritate the scalp or affect hormones.
The findings are still early. They come from one animal study, and no human trials have begun yet. The authors stress that more work is needed to confirm safety, find the best dose, and learn whether the same blood-vessel effect happens in people. If those studies succeed, the sugar gel could also help hair loss after chemotherapy or other types of alopecia.
Frontiers in Pharmacology (official study): “Stimulation of hair regrowth in an animal model of androgenic alopecia using 2-deoxy-D-ribose”
In mice with testosterone-induced hair loss, a gel containing 2-deoxy-D-ribose restored follicle length, diameter, density, and melanin coverage at levels similar to minoxidil. The sugar also boosted the number of skin blood vessels, pointing to angiogenesis (new vessel growth) as the likely mechanism.
University of Sheffield press release – “Cure for male pattern baldness given boost by sugar discovery” – 16 July 2024
Highlights the accidental discovery during wound-healing research, describes the blood-vessel mechanism, and notes the sugar’s low cost and natural origin.
ZME Science coverage – “A common DNA sugar just matched minoxidil in hair regrowth tests on mice”
Summarises the study for a general audience, emphasises parity with minoxidil and the potential for treating chemotherapy-related hair loss, and underscores the need for human trials.
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