Interdental brushes are very small brushes that clean the spaces between teeth. These spaces often hold sticky plaque, which can lead to gum disease if not removed. Gum disease starts when biofilm builds up along the gum line and between teeth. Cleaning these areas every day helps keep gums healthy.
What the science says
Adding an interdental brush to toothbrushing reduces plaque and gum bleeding more than brushing alone. Reviews also find that, for many adults, interdental brushes work as well as or better than floss, mainly when there is enough space for a small brush to pass. A major evidence review for the public notes that brushes may be more effective than floss, and a clinical overview explains that flossing well is hard for many people while brushes are easier to use with good results.
Guidance for everyday use
European periodontal experts advise daily cleaning between teeth. Use an interdental brush wherever it fits without force, and use floss only where spaces are too tight to accept a brush. Oral irrigators can be a useful alternative when brushes do not fit or are not tolerated. Ask a dental professional to size the brush correctly and to show the right technique.
Where TePe fits
TePe is a Swedish maker of interdental brushes used by many dental teams. TePe offers a full range of color coded sizes that follow the international ISO standard for manual interdental brushes, which helps match brush size to the gap between teeth. Angled versions make it easier to reach back teeth. The brand’s professional pages and catalogue state compliance with ISO 16409, and independent literature explains how ISO sizing works.
Special cases
People with braces or dental implants often benefit from interdental brushes because brackets, wires, and implant crowns trap plaque. Studies around implants show interdental brushes can reduce plaque and inflammation when used as part of daily care.
Safety and quality checks
Choose products that meet recognized standards. The ADA sets requirements for manual interdental cleaners, and ISO 16409 defines how sizes are measured and how brushes are tested. These standards help ensure safety and performance.
How to get started
Select the smallest brush that slides through with light contact, do not force it. Move it gently in and out once per space. Clean between teeth once a day, then brush teeth with fluoride toothpaste. If you are unsure about size or technique, ask your dentist or hygienist to help you choose and to show you how to use it.
Cochrane Oral Health – Home use of devices for cleaning between teeth – 2019
This evidence review for the public explains that adding floss or interdental brushes to toothbrushing can reduce gum inflammation and plaque compared with brushing alone. It notes that interdental brushes may be more effective than floss for many people.
Journal of Clinical and Diagnostic Research – An overview of different interdental cleaning aids and their effectiveness – 2019
Narrative review that summarizes clinical trials. It concludes interdental brushes are at least as good as, and often superior to, floss for reducing plaque and gingivitis, and are especially helpful when spaces are wide enough to accept a small brush.
European Federation of Periodontology, for patients – Gum disease prevention
Practical guidance for the public. Clean between teeth daily with interdental brushes, using floss only when spaces are too tight for a brush. Do interdental cleaning before toothbrushing.
Tannlegeforenings Tidende – Recommendations by the European Federation of Periodontology for the public – 2022
Summary of EFP guidance and a network meta analysis. Interdental brushes, chosen by size and shape, are the device of choice for periodontal maintenance. Floss did not improve the effect of brushing alone in that setting, while oral irrigators are an alternative.
Clinical Oral Investigations – Cleansing efficacy of waist shaped inter dental brushes, a randomized controlled crossover study – 2019
Trial comparing brush shapes found that interdental brushes can effectively remove plaque between teeth, and that certain shapes may clean better in specific sites.
International Journal of Dentistry – Clinical efficacy and patients’ acceptance of a rubber interdental bristle versus a metal core brush including TePe – 2014
Randomized clinical trial comparing a rubber bristle device with a standard metal core interdental brush from TePe. Both reduced plaque and bleeding, with differences in user comfort and outcomes by site.
Clinical and Experimental Dental Research – Efficacy of three interdental cleaning methods for peri implant maintenance – 2024
Comparative study around implants found that interdental brushes can lower plaque and inflammation, performing favorably against floss and water flossers in certain measures.
ADA Council on Scientific Affairs – Acceptance Program Requirements, Manual Interdental Cleaners – 2025
Official requirements and clinical protocol guidelines for products seeking ADA evaluation. Outlines safety and efficacy criteria that manufacturers must meet for manual interdental cleaners.
ISO sizing overview – Mapping the product range of interdental brushes, sizes and recommendations – 2020
Explains the ISO 16409 standard used to define interdental brush sizes and performance testing, and why correct sizing matters for safe and effective cleaning.
TePe professional information – Interdental brushes, sizes and ISO compliance – 2022, 2023
TePe states its interdental brushes cover all ISO sizes and are color coded, with angled and original designs to fit different areas of the mouth. Useful for identifying product options, not an independent trial.
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